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San José del Cabo: Proprietors here say that you "graduate" to San José del Cabo after you sow the wild oats of your youth in Cabo San Lucas. It's quieter and more intimate here, and for a cozy, romantic evening, nothing beats San José's nightlife.
The Corridor: This sprawling strip between the two cities is the province of big resorts and their in-house bars. Expect upscale venues (and patrons). A few nightspots not affiliated with any hotel do exist here and are quite popular.
Cabo San Lucas: Had the phrase "What happens in Vegas, stays in Vegas" not already been taken, Cabo San Lucas might have snapped it up. You can experience spring break here, even if you went to college 30 years ago. Quiet Cabo nightlife does exist; you just need to look a bit harder.