In a most unlikely location—among housing projects a good 10-minute walk from the walls—you will find one of the most important religious institutions in Castile. The monastery was founded by Ferdinand and Isabella with the financial assistance of the notorious Inquisitor-General Tomás de Torquemada, who is buried in the sacristy. Further funds were provided by the confiscated property of converted Jews who ran afoul of the Inquisition. Three decorated cloisters lead to the church; inside, a masterful high altar (circa 1506) by Pedro Berruguete overlooks a serene marble tomb by the Italian artist Domenico Fancelli. One of the earliest examples of the Italian Renaissance style in Spain, this influential work was built for Prince Juan, the only son of Ferdinand and Isabella, who died at 19 while a student at the University of Salamanca. After Juan's burial here, his heartbroken parents found themselves unable to return; in happier times, they had often attended Mass here, seated in the upper choir behind a balustrade exquisitely carved with their coats of arms. There are free guided tours at 6 pm on weekends and holidays. The monastery also includes a quirky museum of Asian art collected by missionaries who traveled to the East.