Even the remotest points are an easy one-day drive from Madrid, and northern Spain is superbly covered by freeways.
The drive from Madrid to Bilbao is 397 km (247 miles), about five hours; follow the A1 past Burgos to Miranda del Ebro, where you pick up the AP68. Car rentals are available in the major cities: Bilbao, Pamplona, San Sebastián, and Vitoria. Cars can also be rented at Hondarribia (Fuenterrabía) and the San Sebastián (Donostia) airport. When finding your own way around, you should be aware that the Basque word for calle is kalea. We have standardized our addresses using "Calle," but you might see Kalea on some road signs in residential areas.