Sanlucar de Barrameda

This fishing town has a crumbling charm and is best known for its langostinos (jumbo shrimp) and manzanilla, an exceptionally dry sherry, though it's also known because Columbus sailed from this harbor on his third voyage to the Americas in 1498, and 20 years later Ferdinand Magellan began his circumnavigation of the globe here. The most popular restaurants are in the Bajo de Guía neighborhood, on the banks of the Guadalquivir. Here, too, is a visitor center for Doñana National Park (open daily 9–7 in winter and 9–8 in summer).

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