Funded by the billionaire who owns Christie's Auction House, the François Pinault Foundation had Japanese architect Tadao Ando redesign this fabled customs house—sitting at the punta, or very head, of the Grand Canal—and now home to a changing roster of eyepopping works from Pinault's collection of contemporary art. The streaming light, polished surfaces, and clean lines of Ando's design contrast beautifully with the brick, massive columns, and sturdy beams of the original Dogana. Even if you are cool to contemporary art, a visit is worthwhile just to see Ando's amazing architectural transformation. Be sure to walk down to the punta (point) for a magnificent view of the Venetian basin. Check online for a schedule of temporary exhibitions.