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From Rome or Florence, take the Chiusi-Chianciano exit from the A1 highway (Autostrada del Sole). The town is 13 km (8 miles) west of the Chiusi/Chianciano exit. From Siena, take the SR2 south to San Quirico and then the SP146 to Montepulciano. Tra-In offers bus service from Siena to Montepulciano several times a day. Montepulciano's train station is in Montepulciano Stazione, 10 km (6 miles) away.
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