Florence is on the principal Italian train route between most European capitals and Rome, and within Italy it is served frequently from Milan, Venice, and Rome by Intercity (IC) and nonstop Eurostar trains. Avoid trains that stop only at the Campo di Marte or Rifredi station, which are not convenient to the city center.
Stazione Centrale di Santa Maria Novella. Florence's main train station is in the center of town. Florence. 892021. www.trenitalia.com.