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Coral Princess Cruises runs three- to seven-7 night cruises along the Great Barrier Reef; their Across the Top trip continues to Darwin. There's also a cruise between Darwin and Broome.
Pacific Dawn, Australia's biggest cruise liner, sails various one- and two-week Pacific and New Zealand cruises out of Brisbane. Their Pacific Pearl also cruises the Pacific from Sydney. It's owned by P&O, known in the rest of the world as Princess Cruises.
Princess Cruises' huge Sapphire Princess sails between New Zealand and Australia at the end of its 33-day cruise from Seattle, Washington. The smallerDawn Princess visits Papua New Guinea, Vanuatu, and New Caledonia on its 18-day return cruise to Sydney.
Regent Seven Seas' Seven Seas Mariner docks at several points on Australia's south and east coast on cruises from Asia to Sydney and Auckland. Crystal Cruises' Kangaroos and Kiwis voyage—aboard Crystal Serenity—starts in Sydney and calls at Melbourne and Hobart before ending in Auckland. Crystal Symphony goes up past Brisbane, Cairns, the Barrier Reef, Darwin, and Indonesia to Singapore. Silversea's Silver Whisper has a similar route, and also runs between Australia and New Zealand.
Cunard's Queen Elizabeth sails from New York and San Francisco to Sydney, and calls at Australian ports on round-the-world cruises, too. So do its Queen Mary 2 and Queen Victoria.