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St. Louis to Boston road trip

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Hi, I am planning a raod trip from St. Louis to boston, MA. We are leaving 7 days to take in sights/fun/restaurants/ curiosities (sp?) along the way. What suggestions do people have. We are in the initial stages of planning. The trip is planned for early May 2015 to drive my niece home from her university. Thanks for any insight and suggestions.

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