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Places to stay and things to do along the great river road from MO, IA, IL

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My Husband and I are taking a trip around the first or second weekend in Oct from AR to end destination Lake Carroll, IL. We are wanting to make a weekend out of this trip, its for business you see. We are in AR, the delta region and was wanting to take the great river road through MO, possibly IA, and then IL and was wanting to know about some good places to stay and things to see and do along the way to get the most out of this trip.

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