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Moving to St. Louis for School?

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My friend is considering going to St. Louis University for medical school but is a little concerned about adjusting to life in Seattle. We both grew up in the SF Bay Area and went to college in Los Angeles and haven't much experience with the Midwest. She is an Asian girl and is worried about fitting in culturally as its no where near as diverse as California. Also, the high crime rates are a little bit of a concern. Is it a lively enough place for someone in their early/mid 20s? Does anyone have any advice that I could pass on? Thanks for your help!

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