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Estes Park/ altitude adjustment

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We will begin our two weeks in Colorado in September with four nights in Estes Park. We are both "over 60", reasonably healthy. We live at sea level. We are wondering if we should spend our first night in Boulder, instead of in Estes Park to allow our bodies to adjust to the altitude? If this is really not necessary, we want to just head directly from Denver airport to Estes Park. Also, can fellow travelers please suggest the most direct driving route from Denver airport to Estes Park? For our first day we hope to avoid steep, narrow roads with drop-offs and no guardrails. Thanks.

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