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Driving Baltimore to Boston - best route and time-of-day?

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I'll be driving straight through from Baltimore to Boston on Wednesday of next week, and am looking for the speediest and least stressful way to do it. The time for departure is flexible to avoid rush hours... though driving all night (undoubtedly the "easiest" time) is not appealing.

Mapquest routes me up I-95 to New Haven, then on I-91, then I-84, then I-90

Any thoughts?

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