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Salta and Northwest Argentina Itinerary Help

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I am planning a first time trip to Argentina in early April, during which I will have 5 nights in the Northwest. I am having a terrible time deciding where to go, it all sounds wonderful... but with the time I have, I can't do it all at a pace I will enjoy. I must spend my last night in Salta, as I will have a very early flight to El Calafate the next morning. So the question is, go north of Salta, or south to explore? I am interested in Purmamarca, Humahuaca and Cafayate. My two options, as I see them, are go north to Purmamarca and Humahuaca, spending 3 or 4 nights between them, and back to Salta for the last night, or go to Cafayate and environs for 3 or 4 nights and Salta for the last 1 or 2.

Here is what I am looking for: beautiful natural scenery, with the opportunity to do some hiking, biking, or other outdoor activities, quaint towns/villages to nose around in, and a taste of the Andean culture. Visiting wineries would be wonderful, but not essential. I'd love to hear your thoughts! Also, if I've missed something in the region that fits the above bill, please let me know! Many thanks in advance!

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