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Patagonia

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There was no S. American category- shame on you!) so I'm entering here.
;I would love to visit Patagonia in November or December avoiding the crowds of Christmas. I will be in Santiago visiting my daughter, have never cruised and am fascinated by Alaska and Patagonia disappearing. Can we leave from Vena del Mar rather than Buones Aries?
Is Patagonia much different than Alaska? I'd love to hear from anyone about options and specifics about what cruise lines are best for a senior citizen and 25 year old daughter.
Thanks!

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