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Panama planning

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I'm planning a 7-day trip to Panama and am looking for advice on things to do and things to avoid. Our main interests are history and architecture, beaches and nature preserves, great seafood and local cuisine, and indigenous cultures.

We are thinking of staying in Panama City. I'm not sure if Casco Viejo is the right place to stay. As long as it's relatively safe and has some restaurants and bars open at night it would suit our needs. It sounds like a more dilapidated version of Old San Juan. Campeche, Mexico, is one of our favorite places so if it's comparable, that would be perfect.

We're also thinking of going to Isla Taboga for an overnight trip. It sounds really peaceful and beautiful. We're wondering if going to Portobelo would be worth the trip. We probably won't rent a car if there is reliable enough bus service. I hear it's only a couple hour ride.

Would love to hear what others think about these places and others I'm not aware of. Thanks in advance.

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