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Panama home base

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My wife and I, along with two other couples, hope to spend a week in Panama sometime in February. We are in our mid 60s and looking for a relaxing vacation focused on beach, natural scenery (including bird-watching) and perhaps a slight bit of snorkeling and fishing. We also very much enjoy the arts - concerts, good theatre, dance, etc. Finally, we will want to take the obligatory tour of the Panama Canal.

What might be the best home base for such a week?

Thanks.

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