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Driving in C.America

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DH and I are wondering what people's opinion is on driving down the Pacific side from Guatamala to Panama then up the east coast thru Nicaragua and Honduras to Belize. Is that not a safe idea, or should we consider driving thru some parts and flying thru other less 'desirable" areas. We would stay in hotels or b&b's, and rent a car. Does anyone have a suggestion on some other form of travel that would be safer and still see a lot of the country, without belonging to a bus tour group?

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