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Travel from Amsterdam to Prague

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Hi,

I am looking to travel from Amsterdam to Prague on May 12th.
I am looking for the cheapest and most painless way to go.
I found flights for around $140
A bus for $95....seems like it might be crazy to take a bus for 12 hours
The train has been the biggest problem so far, I've been looking at the Bahn website, which is a bit confusing. I've either seen crazy expensive tickets, or options with transfers, where you can't see the prices or how to buy them.

Any advice on how to book this trip would be greatly appreciated!

Thank you

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