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Transport from Nuremberg to Prague

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We are a two couples taking a Viking River cruise. After the cruise we are going to Prague. Other than using Viking, we are trying to determine other ways to travel between the two cities.

1. How difficult is driving a car in the Czech Republic?

2. Opinions on train travel vs. bus travel from Nuremberg to Prague ? Ease of travel, comfort, cost?


Luggage handling on each one? I tend to bring too much luggage. I really want to make it easy on my husband so are there luggage restrictions/suggestions for train and bus travel. We'll be gone for 3 and 1/2 weeks.

3. Best and most reputable website to book train and/ or bus tickets from Nuremberg to Prague?

Thank you for your help.

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