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Train Travel from Rome to Siena

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There are 6 in our group and we are flying into Rome and staying for 4 days and traveling to Siena, then to the Amalfi Coast. We are contemplating renting a vehicle for Tuscany and Amalfi and want to know if we can take train from Rome, rent a vehicle in Siena for a week. We are concerned that we need a large vehicle to transport our luggage from location to location, however, we would not require that large of a vehicle for our two weeks' stay. Any thoughts on this would be most appreciated. By the way, we were quoted $2,000 for a vehicle large enough to accommodate us and our luggage for the entire 2 weeks.

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