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First day in Rome after little to no sleep

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We are arriving in Rome at 7am after a transatlantic flight from US. I doubt we will get much sleep. We can not check into our hotel until 2pm so I am wondering what are folks usually up for on that first day. I want to make the most of it without overdoing it.

I was thinking of the Pantheon area or Trastevere.

My son is really excited about the coliseum but I thought that might be best for Day 2.

When does the jet lag usually set in?

I am traveling with my son (age 10) and sister and Mother (active 70 year old).

Thanks!
Amy

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