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Can you recommend a scenic drive between Siena and Orvieto?

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On day 9 of our 10-day trip to Italy we will be checking out of our hotel in Florence. We plan to drive to Siena and then drive to our hotel in Orvieto. We leave at 7:30 AM for our FCO flight at 12:20 on day 10. Do we have time for a scenic drive through Tuscany? Can anyone suggest a route? Thank you.

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