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Bus travel from Rome to poggibonsi in Italy

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Going to Rome on the 10th of Sept. It sounds as if traveling by bus out to the Tuscany region is a good idea from what I have been reading. We are staying in a villa in Poggibonsi. My question is: What town should we go to on the bus from Rome? Can we get all the way to Poggibonsi from Rome by bus? Will it be the same Sena bus or do we have to change to another type of bus somewhere and where?

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