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Best way to reach Tiburtina Bus station Rome?

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Two of us need to catch a bus ( with our luggage) at 7:30 am from Tiburtina Bus station, travelling to Urbino..

We will be staying at an apartment 10 minute walk from Termini Train station.

Have not used the Metro system before.

Would we be better off taking a cab or train to Tiburtina Bus station.

Any tips on using the Metro to reach Tiburtina?

It will be on a Monday if that makes any difference.

Thanks in advance!

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