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11 day itinerary for Rome-Florence-Siena-Venice

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Thanks to all for advice on my last posted topic. I found direct flights into Rome and out of Venice. Great time saver. I chose to end in Venice for a more relaxed end to my vacation and because the flight offered out of Venice is at 11:45 and not one of those dreadful early morning flights.

Now I'm working on my hotel planning. The change in flight plans has added an extra day to my trip, and I'd like a few pointers on how to allocate my days, particularly between Rome and Florence. I'm curious about the charms of Siena so I'm think of doing a day trip. Regarding Siena, I am most interested in strolling around and enjoying nice scenery -- I can hit any must see places as necessary. Staying a night is a consideration, but only if it would be easier.

Option 1: Bus in a.m. on Day 5 from Rome to Siena (3.5 hours? and a little long for my liking), where I can then spend a night and the next day, and then take a bus to Florence in the late afternoon. The length of the bus trip does not appeal to me. Alternatively, if I take train to Florence from Rome as in option 2, then I can cut maybe 1.5 hours from the Rome-Siena bus trip, which will all average out later with bus trips between Florence-Siena.

Option 2: Train from Rome to Florence and do a day trip at some point during my Florence stay to Siena. This has potential since I don't want to overdose on museums and if I can take a late evening bus from Siena back to Florence.

Option 3: Train from Rome to Florence. While in Florence, take bus to Siena and spend a night and back to Florence for another day before taking train to Venice. Seems a little inconvenient due to hotel changes.

So far, option 2 is in the lead since it cuts out one hotel change.

Day 1 (Monday): Arrive in Rome by 8:00 a.m.
Day 2: Rome
Day 3: Rome
Day 4: Rome
**Day 5 (Friday): Rome to Siena or Rome to Florence?
Day 6 (Sat.):Florence
Day 7 (Sun.): Florence
Day 8 (Mon.): Florence
Day 9: Venice (Train from Florence in a.m.)
Day 10: Venice
Day 11: Venice
Day 12: leave for home

My main question is how to allocate days between Rome and Florence and what to do with Siena. In Rome, I'll likely do one day for Vatican, likely another day for Coloseum/Forum/Pantheon or I'll wonder if I'm missing out on this stuff, then need to see Borghese gallery and explore some interested neighborhoods and catacombs on another day(s). I'm still researching other things to do in Rome and the different catacombs and whether I would have any interest in short trip to either Tivoli (probably not) or Ostia Antica. My trip starts in the last week of March.

I'm not sure if I have too much time allocated to Florence or not. I plan on hitting main art galleries in Florence, particularly for paintings and great sculptures, and then having a little time to relax. I'm aware that Uffizi and some other sites are not open on Monday in Florence as well. Not yet sure about limitations that certain days may have in Siena, other then possibly less frequent buses on the weekends.

Any pointers?

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