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10 Days In Italy - Itinerary Help?

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I will be going to Italy in October with my mother for my 30th B-day. I have been trying to put together an itinerary for a month or so. This is a ruff draft and a few questions. I am sure I will have more.

Leave Thurs. night arriving Fri. morning (11 am)
Day 1 Fri: Venice (overnight)
Day 2 Sat: Venice (overnight)
Day 3 Sun: Leave Venice in AM for Florence (overnight)
Day 4 Mon: Florence (overnight)
Day 5 Tue: Florence (overnight? possibly leave at night and head to Rome - if not first thing in the AM)
Day 6 Wed: Rome (overnight)
Day 7 Thur: Rome (overnight)
Day 8 Fri: Rome (overnight)
Day 9 Sat: Rome (overnight)
Day 10 Sun: Leave Rome in the evening


Questions: Should I stay 2 nights in Venice, 3 nights in Florence and 4 nights in Rome? Any suggestions where to stay in Venice (budget)? Will I have time in Florence for a day or 1/2 day trip to Pisa and see Accademia, Uffizi, Duomo? How should I map it out? Day trip to Pompeii from Rome?

I am confused about train travel between venice - florence and florence - rome? Do I have to book tickets ahead? Is it easy to travel on buses/trains (I think I'm most nervous about that and getting lost)

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