My suggestions would be as follows:

1. A limousine service, this is easiest but most expensive. I think about HK$700 but check with sites. For a private limo service go to http://www.hongkongairport.com/eng/aguide/limousine.html. I have used Parklane for years and they are very good. Any limo service will meet you just outside baggage claim and bring you right to the car. Very nice service. The drive will take about 30 minutes. We have little traffic, so not an issue.

2. A taxi, this will be about HK$400 give or take. A small charge for the luggage. No tipping is required or expected. The taxi will take about 30 minutes.

3. Airport Express train to Hong Kong Station and then a taxi to the hotel. This is quite easy to do, and even with a lot of luggage, quite manageable. The train journey is 28 minutes. Train fare is about HK$100 per person; there are some deals if you buy an Octopus card, you can look into that, but assume HK$100 as a ballpark. You can roll luggage cars onto the train and there is a luggage area in each car, so you don’t really have to schlep bags a whole lot. There will be luggage carts when you arrive into the train station on Hong Kong Island and you can roll luggage to the taxi rank. The taxi rank is just opposite where the train arrives, so again is very easy. The taxi fare to Wellington Street will be about HK$25 at most, again with a small luggage charge. The drive will take something under 10 minutes.

For infomration on the Airport Express train see http://www.hongkongairport.com/eng/transport/to-from-airport/airport-express.html

It is possible to walk from the Airport Express train station in Hong Kong to your hotel via a overhead pedestrian walkway most of the way, but at the end you will have to use stairs and will have a short downhill walk to get to the hotel, so this may not be a good option for you. (It may also be a pain with more than minimal luggage.) The walk would take 15 minutes or so. If you want directions for a walk, repost and I will provide them.

There are public bus options form the airport to the main bus terminal which is not far from the hotel, but frankly, I think this would be a hassle, although quite a bit cheaper. If cost is a big issue, let me know and I can provide bus numbers and directions.

The hotel is in a very central location for sightseeing so should work out well for you.